CHBE680

Physics at nano/micro scales. Biomolecular building blocks. Simplest biomolecular assembly: protein folding. Nanoscale intermolecular interactions important in biology. Protein-ligand binding. Protein higher-order assembly: filaments, networks. Protein filaments and motility. DNA, RNA and their assembly assisted by proteins. Viral capsid assembly. Lipid assembly into micelles, bilayers. Lipid-protein co-assembly in membranes. Lipid and polymer-based carriers useful in medicine. Antimicrobial therapies. Targeted cancer therapy. Ideal properties of nanocarriers in terms of size, charge, and surface chemistry.